Prototype 2 is a first person game. It is developed by Canadian studio Radical Entertainment. The sequel is published by Activision.
Prototype 2 Demo | PC Game Free Download Full Version Full Game Requirements Minimum Requirements: Video Game Controllers: Trackball, keyboard, joysticks, gamepad, mouse Required Windows OS: Windows 7, 8, 10, Vista, XP,...Pilot study of a new multi-channel intra-operative MRI to guide epilepsy surgery.
The current intra-operative methods for mapping the seizure onset zone (SOZ) in patients with intractable epilepsy are based on the precise identification of the "reactive" epileptic cortex, which is considered to be equivalent to the "lesional" cortex. We performed a pilot study in a small cohort of patients with epilepsy to test the feasibility and accuracy of a new intra-operative imaging method, called "BrainNavigator," which is based on a newly developed multi-channel intra-operative MRI. The brain regions with a neuronal activity increase and a possible epileptic onset zone were determined by using a new software that performs automatic pre-processing of fMRI data. After craniotomy, we performed a combined neuronavigation (BrainNavigator) and intra-operative electrocorticography (ECoG) with two ECoG electrodes in each patient. In all patients, we found an ECoG signal change in relation to the electrode positions on the brain surface as indicated by the BrainNavigator. In seven patients, the BrainNavigator was able to detect and localize the epileptic onset zone by using a combination of the signal intensity changes of the ECoG signals, whereas in two patients the exact localization of the SOZ could not be achieved. Our data support the feasibility of a combined neuronavigation and intra-operative ECoG. Nevertheless, several technical limitations are still hampering the clinical use of this method.Global and local genetic structure of the opportunistic pathogen Rhodococcus erythropolis DAPP-PG37.
Rhodococcus erythropolis DAPP-PG37 is a soil-borne organism, which causes blossom blight in plants. R. erythropolis DAPP-PG37 produces the antibiotic nocathiacin which is used as a medicine against parasitic diseases. Here, a genome-wide analysis of genetic diversity and population structure of R. erythropolis DAPP-PG37 was performed using a collection of 93 strains originating from a wide geographic and host ac619d1d87
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